About OncoDB.HCC

HCC is the sixth most common cancer worldwide and the third most common cause of death from cancer because of the extremely low survival rate. To accelerate the research of HCC, we created OncoDB.HCC as the first comprehensive oncogenomic database for HCC.  It effectively integrate following three datasets from public references to provide multi-dimension view of current HCC studies.
    Chromosome aberration studies
        Genome-wide loss of heterozygosity (LOH)
        Comparative genome hybridization (CGH)
    Gene expression studies
        Microarrays
        Proteomic study
        Experimental data of gene expression
    HCC model organisms
        QTL of HCC Mouse models
        QTL of HCC Rat models

The integration and displays of OncoDB.HCC in views of genome, transcriptome and proteome are primarily based on annotations and data from databases of
    Ensembl
    NCBI
    Stanford MicroArray Database

This database is part of the research project of Institute of Biomedical Sciences, Academia Sinica.

To cite OncoDb.HCC
   Nucleic Acids Research, 2007, Vol. 35, Database issue D727-D731.

Quick Search
   Display major aberrations of HCC

Commom genomic aberration regions and significant genes with altered expression profiles selected by OncoDB.HCC. ( selection criteria and experimental validations )

Common genomic aberration regions
Comparative HCC regions
HCC significant genes
    Display whole chromosome  

Select a chromosome and display oncogenomic data within the chromosome. To display certain chromosome region and to use karyotype or STS marker, please use advance search - chromosoem region option on the left side.

    Chromosome    
   Display queried gene and reginal data
Select the feature and input keyword to select human gene or markers. Then choose to display expression data of the gene or chromosome region around the human gene/marker. To use mouse or rat gene/markers as selection feature, please use advance search - region around gene option on the left side.
      +/- Mb