OncoDB.HCC Expression View

Gene name : SYPL1
Ensembl ID ENSG00000008282
Description Synaptophysin-like protein 1 (Pantophysin). [Source:Uniprot/SWISSPROT;Acc:Q16563]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
38 percent with 2 folds change ( 21 up and 1 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 7 from 100518194 bp to 110540293 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 770444 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.11) HK1 (0.07) HK3 (0.49) HK4 (1.10) HK5 (-0.36) HK7 (0.84) HK9 (0.36) HK11 (1.26) HK12 (0.16) HK13 (1.29) HK14 (0.60) HK15 (1.29) HK16 (0.98) HK18 (0.45) HK19 (-0.63) HK20 (1.09) HK21 (0.45) HK22 (1.32) HK24 (0.77) HK27 (0.52) HK28 (0.87) HK29 (0.59) HK31 (1.54) HK33 (0.08) HK36 (0.38) HK37 (1.83) HK38 (1.23) HK39 (-0.23) HK42 (-0.49) HK46 (-0.06) HK47 (1.32) HK49 (2.15) HK62 (-2.44) HK63 (0.35) HK64 (2.22) HK67 (1.05) HK84 (1.25) HK85 (0.27) SF1 (-0.04) SF12 (1.17) SF15 (2.19) SF17 (1.94) SF18 (-0.36) SF21 (0.03) SF22 (-0.36) SF23 (-0.55) SF32 (0.85) SF34 (-0.65) SF35 (-0.36) SF3 (0.43) SF30 (0.82) HK2 (0.38) HK23 (1.09) HK41 (1.00) SF4 (-0.12) SF8 (1.04) SF9 (0.13)