OncoDB.HCC Expression View

Gene name : HFE
Ensembl ID ENSG00000010704
Description Hereditary hemochromatosis protein precursor (HLA-H). [Source:Uniprot/SWISSPROT;Acc:Q30201]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
24 percent with 2 folds change ( 8 up and 5 down in 53 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence mutation     Method -- Mutation    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 6 from 21195427 bp to 31205035 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 125808 -- IMAGE clone locate on exon ( tblastx )
1161797 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.66) HK1 (-0.51) HK3 (-0.37) HK4 (0.36) HK5 (-0.33) HK7 (0.05) HK9 (0.58) HK11 (-0.36) HK12 (0.42) HK13 (-0.30) HK14 (0.36) HK15 (0.04) HK16 (0.12) HK18 (1.03) HK19 (0.42) HK20 (-0.51) HK21 (0.81) HK22 (0.12) HK24 (1.44) HK27 (0.00) HK28 (1.14) HK29 (0.89) HK31 (-1.41) HK33 (-1.12) HK36 (0.34) HK37 (0.13) HK38 (1.74) HK39 (0.51) HK42 (2.45) HK46 (0.37) HK47 (0.00) HK49 (0.49) HK62 (0.04) HK63 (0.50) HK64 (2.11) HK67 (0.00) HK84 (0.61) HK85 (0.68) SF1 (-1.10) SF12 (-0.41) SF15 (-0.37) SF17 (0.26) SF18 (0.61) SF21 (-0.91) SF22 (1.10) SF23 (-0.26) SF32 (-0.85) SF34 (1.51) SF35 (0.12) SF3 (0.00) SF30 (-0.31) HK2 (0.43) HK23 (0.15) HK41 (-0.02) SF4 (0.24) SF8 (0.00) SF9 (-1.54)