OncoDB.HCC Expression View

Gene name : DCN
Ensembl ID ENSG00000011465
Description Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40). [Source:Uniprot/SWISSPROT;Acc:P07585]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
20 percent with 2 folds change ( 8 up and 0 down in 40 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 12 from 85063167 bp to 95100937 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 366554 -- IMAGE clone locate on exon ( blastn )
CH2 (0.00) HK1 (0.32) HK3 (0.64) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (0.31) HK12 (-0.27) HK13 (-0.00) HK14 (0.34) HK15 (0.33) HK16 (0.47) HK18 (0.90) HK19 (-0.35) HK20 (0.09) HK21 (-0.31) HK22 (-0.59) HK24 (1.15) HK27 (0.20) HK28 (1.04) HK29 (0.33) HK31 (0.42) HK33 (0.84) HK36 (0.50) HK37 (1.79) HK38 (0.00) HK39 (-0.67) HK42 (0.78) HK46 (-0.04) HK47 (0.00) HK49 (-0.48) HK62 (0.00) HK63 (1.06) HK64 (0.93) HK67 (0.00) HK84 (0.00) HK85 (-0.58) SF1 (0.89) SF12 (0.00) SF15 (0.00) SF17 (2.61) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (-0.11) SF32 (-0.05) SF34 (1.02) SF35 (0.00) SF3 (1.52) SF30 (0.00) HK2 (0.28) HK23 (0.42) HK41 (0.79) SF4 (-0.61) SF8 (-0.00) SF9 (3.09)