OncoDB.HCC Expression View

Gene name : ERCC1
Ensembl ID ENSG00000012061
Description DNA excision repair protein ERCC-1. [Source:Uniprot/SWISSPROT;Acc:P07992]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
7 percent with 2 folds change ( 3 up and 1 down in 52 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 19 from 45604712 bp to 55619017 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 120468 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.20) HK1 (-0.13) HK3 (-0.39) HK4 (0.03) HK5 (-0.47) HK7 (-0.41) HK9 (0.35) HK11 (0.33) HK12 (0.24) HK13 (0.51) HK14 (0.46) HK15 (0.57) HK16 (0.24) HK18 (-0.04) HK19 (-1.14) HK20 (0.54) HK21 (-0.12) HK22 (0.31) HK24 (0.02) HK27 (-0.77) HK28 (0.02) HK29 (0.98) HK31 (0.07) HK33 (-0.11) HK36 (0.17) HK37 (0.83) HK38 (-0.11) HK39 (0.00) HK42 (-0.27) HK46 (0.18) HK47 (-0.49) HK49 (0.00) HK62 (-0.66) HK63 (0.33) HK64 (0.67) HK67 (1.17) HK84 (0.59) HK85 (0.05) SF1 (-0.33) SF12 (1.27) SF15 (-0.20) SF17 (0.45) SF18 (0.35) SF21 (-0.08) SF22 (0.61) SF23 (0.00) SF32 (0.82) SF34 (0.00) SF35 (0.30) SF3 (3.80) SF30 (0.49) HK2 (0.70) HK23 (0.00) HK41 (0.73) SF4 (-0.27) SF8 (0.00) SF9 (0.34)