OncoDB.HCC Expression View

Gene name : RUNX3
Ensembl ID ENSG00000020633
Description Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 [Source:Uniprot/SWISSPROT;Acc:Q13761]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
27 percent with 2 folds change ( 1 up and 10 down in 40 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- Methylation    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 1 from 20098596 bp to 30164062 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 291478 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.02) HK3 (-0.71) HK4 (-0.97) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (0.09) HK12 (-0.55) HK13 (0.16) HK14 (0.80) HK15 (0.01) HK16 (-0.80) HK18 (0.16) HK19 (-1.58) HK20 (-0.77) HK21 (-0.09) HK22 (-0.24) HK24 (-1.69) HK27 (-0.44) HK28 (-2.01) HK29 (-0.99) HK31 (-1.08) HK33 (-0.41) HK36 (-1.28) HK37 (0.00) HK38 (0.12) HK39 (-0.13) HK42 (-1.51) HK46 (-0.51) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (0.19) HK64 (0.00) HK67 (0.00) HK84 (-0.27) HK85 (-1.10) SF1 (-0.72) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (-4.54) SF32 (0.00) SF34 (0.08) SF35 (-0.63) SF3 (0.00) SF30 (0.15) HK2 (-1.36) HK23 (-0.55) HK41 (-1.38) SF4 (0.25) SF8 (-0.32) SF9 (1.11)