OncoDB.HCC Expression View

Gene name : VIM
Ensembl ID ENSG00000026025
Description Vimentin. [Source:Uniprot/SWISSPROT;Acc:P08670]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 11 up and 5 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene    
Display nearby genome region Chr 10 from 12311283 bp to 22319598 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 306621 -- IMAGE clone locate on exon ( tblastx )
590323 -- IMAGE clone locate on exon ( tblastx )
840511 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.25) HK1 (-0.27) HK3 (1.22) HK4 (-0.17) HK5 (-0.01) HK7 (0.42) HK9 (0.14) HK11 (1.91) HK12 (-1.05) HK13 (0.26) HK14 (0.99) HK15 (0.61) HK16 (1.55) HK18 (0.08) HK19 (0.50) HK20 (-0.38) HK21 (1.85) HK22 (-0.43) HK24 (0.85) HK27 (2.16) HK28 (-0.83) HK29 (-1.29) HK31 (1.79) HK33 (-0.10) HK36 (0.46) HK37 (0.48) HK38 (2.73) HK39 (0.96) HK42 (-0.74) HK46 (-0.39) HK47 (1.20) HK49 (2.10) HK62 (-0.80) HK63 (-2.81) HK64 (-1.02) HK67 (0.11) HK84 (0.44) HK85 (0.24) SF1 (-0.14) SF12 (0.29) SF15 (0.51) SF17 (-0.30) SF18 (0.73) SF21 (0.86) SF22 (0.70) SF23 (-0.97) SF32 (-0.09) SF34 (-0.18) SF35 (1.71) SF3 (-0.45) SF30 (0.74) HK2 (-0.90) HK23 (-0.29) HK41 (-0.13) SF4 (-0.43) SF8 (0.48) SF9 (1.66)