OncoDB.HCC Expression View

Gene name : FAS
Ensembl ID ENSG00000026103
Description Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen). [Source:Uniprot/SWISSPROT;Acc:P25445]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
46 percent with 2 folds change ( 0 up and 24 down in 52 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 10 from 85739206 bp to 95765521 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 714213 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-1.06) HK3 (-0.85) HK4 (-1.55) HK5 (-0.54) HK7 (-0.24) HK9 (-0.89) HK11 (-0.92) HK12 (-0.50) HK13 (-1.18) HK14 (-2.60) HK15 (-1.38) HK16 (-0.25) HK18 (-0.53) HK19 (-1.54) HK20 (0.65) HK21 (-1.25) HK22 (-0.91) HK24 (-0.73) HK27 (-1.59) HK28 (-0.83) HK29 (-0.97) HK31 (0.62) HK33 (-1.15) HK36 (0.16) HK37 (-1.26) HK38 (-0.40) HK39 (-1.45) HK42 (-0.47) HK46 (-1.47) HK47 (-1.24) HK49 (-0.60) HK62 (0.00) HK63 (-0.61) HK64 (-1.31) HK67 (-1.23) HK84 (-1.33) HK85 (0.28) SF1 (-0.40) SF12 (0.00) SF15 (0.05) SF17 (0.37) SF18 (-2.27) SF21 (-1.27) SF22 (0.00) SF23 (-0.44) SF32 (-1.01) SF34 (0.00) SF35 (-1.70) SF3 (-1.71) SF30 (-1.50) HK2 (-1.93) HK23 (0.01) HK41 (-0.30) SF4 (-0.74) SF8 (-0.46) SF9 (-1.43)