OncoDB.HCC Expression View

Gene name : HSPA5
Ensembl ID ENSG00000044574
Description 78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78). [Source:Uniprot/SWISSPROT;Acc:P11021]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern, RT-PCR, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Honda et al., Gastroenterology 120:955(2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
up     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene    
Display nearby genome region Chr 9 from 122036953 bp to 132043430 bp