OncoDB.HCC Expression View

Gene name : PRSS8
Ensembl ID ENSG00000052344
Description Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain]. [Source:Uniprot/SWISSPROT;Acc:Q16651]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
74 percent with 2 folds change ( 6 up and 34 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Links Entrez Gene    
Display nearby genome region Chr 16 from 26050284 bp to 36054320 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1475659 -- IMAGE clone locate on exon ( blastn )
132636 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.21) HK1 (-1.22) HK3 (0.14) HK4 (-2.93) HK5 (0.00) HK7 (-0.31) HK9 (1.15) HK11 (0.90) HK12 (-1.42) HK13 (-1.41) HK14 (-1.81) HK15 (-0.43) HK16 (-0.88) HK18 (-0.10) HK19 (0.29) HK20 (-1.01) HK21 (0.19) HK22 (-1.11) HK24 (-2.91) HK27 (-3.34) HK28 (1.69) HK29 (0.08) HK31 (-1.69) HK33 (2.42) HK36 (-2.42) HK37 (-2.04) HK38 (-2.63) HK39 (-2.13) HK42 (2.15) HK46 (-2.50) HK47 (-2.75) HK49 (0.90) HK62 (0.00) HK63 (0.56) HK64 (-2.70) HK67 (-2.56) HK84 (-3.12) HK85 (-4.35) SF1 (-1.62) SF12 (-2.29) SF15 (-4.00) SF17 (0.00) SF18 (1.34) SF21 (1.20) SF22 (-1.30) SF23 (-1.69) SF32 (-1.19) SF34 (-1.43) SF35 (0.13) SF3 (0.29) SF30 (-0.09) HK2 (-2.02) HK23 (-2.12) HK41 (-2.41) SF4 (-2.63) SF8 (-3.28) SF9 (-2.80)