OncoDB.HCC Expression View

Gene name : NGFR
Ensembl ID ENSG00000064300
Description Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen). [Source:Uniprot/SWISSPROT;Acc:P08138]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
70 percent with 2 folds change ( 0 up and 31 down in 44 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 17 from 39927654 bp to 49947356 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 154790 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.90) HK1 (-2.52) HK3 (-1.71) HK4 (-3.86) HK5 (0.00) HK7 (-1.80) HK9 (0.00) HK11 (-0.22) HK12 (-0.69) HK13 (-2.38) HK14 (-2.84) HK15 (-1.80) HK16 (-0.57) HK18 (-1.16) HK19 (0.00) HK20 (-3.85) HK21 (-0.55) HK22 (-0.15) HK24 (-1.79) HK27 (-1.42) HK28 (-1.66) HK29 (-0.26) HK31 (-1.52) HK33 (-1.73) HK36 (-1.55) HK37 (-3.74) HK38 (-2.31) HK39 (-2.30) HK42 (-0.99) HK46 (-4.01) HK47 (0.00) HK49 (-0.29) HK62 (0.45) HK63 (-0.54) HK64 (0.00) HK67 (0.00) HK84 (-1.60) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (-1.15) SF17 (-1.85) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (-2.06) SF32 (-1.95) SF34 (0.03) SF35 (0.00) SF3 (-2.41) SF30 (-2.52) HK2 (-2.07) HK23 (-1.47) HK41 (-2.95) SF4 (0.49) SF8 (-0.16) SF9 (-3.41)