OncoDB.HCC Expression View

Gene name : YBX1
Ensembl ID ENSG00000065978
Description Nuclease sensitive element-binding protein 1 (Y-box-binding protein 1) (Y-box transcription factor) (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (Enhancer factor I subunit A) (EFI-A) (DNA-binding protein B) (DBPB). [Source:Uniprot/SWISSPROT;Acc:P67809]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
42 percent with 2 folds change ( 19 up and 5 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Iizuka et al., Oncogene 22:3007 (2003)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 1 from 37920659 bp to 47940660 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 949932 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.18) HK1 (-0.08) HK3 (1.10) HK4 (3.18) HK5 (-0.10) HK7 (-0.55) HK9 (-0.26) HK11 (1.44) HK12 (-0.32) HK13 (2.35) HK14 (2.15) HK15 (1.50) HK16 (1.02) HK18 (1.68) HK19 (1.66) HK20 (-0.57) HK21 (1.25) HK22 (1.63) HK24 (0.67) HK27 (0.91) HK28 (0.93) HK29 (0.27) HK31 (0.22) HK33 (-0.17) HK36 (0.43) HK37 (2.17) HK38 (0.90) HK39 (-0.23) HK42 (1.37) HK46 (1.00) HK47 (2.35) HK49 (0.59) HK62 (-2.35) HK63 (0.02) HK64 (0.36) HK67 (0.21) HK84 (2.32) HK85 (0.30) SF1 (0.66) SF12 (0.11) SF15 (0.22) SF17 (-2.11) SF18 (-1.08) SF21 (-1.99) SF22 (-1.18) SF23 (-0.23) SF32 (-0.74) SF34 (-0.22) SF35 (1.48) SF3 (0.54) SF30 (1.39) HK2 (-0.83) HK23 (-0.73) HK41 (0.39) SF4 (0.47) SF8 (-0.17) SF9 (2.09)