OncoDB.HCC Expression View

Gene name : KLF6
Ensembl ID ENSG00000067082
Description Krueppel-like factor 6 (Core promoter element-binding protein) (B- cell-derived protein 1) (Proto-oncogene BCD1) (Transcription factor Zf9) (GC-rich sites-binding factor GBF). [Source:Uniprot/SWISSPROT;Acc:Q99612]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
45 percent with 2 folds change ( 4 up and 22 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence mutation     Method -- Mutation    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 10 from 0 bp to 8817467 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 360436 -- IMAGE clone locate on exon ( tblastx )
510381 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.28) HK1 (-0.48) HK3 (0.05) HK4 (-2.11) HK5 (-0.08) HK7 (-2.21) HK9 (-1.89) HK11 (-1.05) HK12 (-1.38) HK13 (-1.26) HK14 (-1.97) HK15 (-1.10) HK16 (-0.96) HK18 (-0.37) HK19 (-0.65) HK20 (-0.71) HK21 (1.32) HK22 (-0.98) HK24 (-1.21) HK27 (-0.25) HK28 (-0.22) HK29 (0.17) HK31 (-2.10) HK33 (1.51) HK36 (0.04) HK37 (-1.12) HK38 (-1.67) HK39 (-1.52) HK42 (-1.46) HK46 (-0.53) HK47 (-0.84) HK49 (-0.06) HK62 (-0.35) HK63 (-1.73) HK64 (-2.72) HK67 (-0.52) HK84 (-0.74) HK85 (-0.92) SF1 (-1.04) SF12 (-0.81) SF15 (-1.35) SF17 (1.17) SF18 (-0.10) SF21 (0.74) SF22 (-0.26) SF23 (-0.88) SF32 (-1.25) SF34 (-0.18) SF35 (-1.51) SF3 (-0.03) SF30 (-1.31) HK2 (-0.40) HK23 (-0.86) HK41 (-0.42) SF4 (-1.05) SF8 (-0.18) SF9 (1.09)