OncoDB.HCC Expression View

Gene name : EDN1
Ensembl ID ENSG00000078401
Description Endothelin-1 precursor (Preproendothelin-1) (PPET1) [Contains: Endothelin-1 (ET-1); Big endothelin-1]. [Source:Uniprot/SWISSPROT;Acc:P05305]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
53 percent with 2 folds change ( 0 up and 15 down in 28 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 6 from 7398582 bp to 17405413 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 47359 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.00) HK3 (-0.43) HK4 (-0.48) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (0.00) HK12 (-1.75) HK13 (-1.71) HK14 (-1.03) HK15 (-1.15) HK16 (-0.47) HK18 (-0.81) HK19 (-1.11) HK20 (-0.63) HK21 (-0.23) HK22 (-1.14) HK24 (0.00) HK27 (-0.32) HK28 (-0.19) HK29 (-0.26) HK31 (-1.03) HK33 (0.61) HK36 (0.00) HK37 (0.00) HK38 (-1.43) HK39 (-0.51) HK42 (0.00) HK46 (0.00) HK47 (0.05) HK49 (0.00) HK62 (0.00) HK63 (0.00) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (-1.71) SF12 (0.00) SF15 (0.00) SF17 (-0.29) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (0.00) SF34 (0.00) SF35 (0.00) SF3 (0.00) SF30 (-1.50) HK2 (-2.35) HK23 (-1.46) HK41 (0.00) SF4 (-1.02) SF8 (-1.11) SF9 (-1.88)