OncoDB.HCC Expression View

Gene name : PAFAH1B3
Ensembl ID ENSG00000079462
Description Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma). [Source:Uniprot/SWISSPROT;Acc:Q15102]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
23 percent with 2 folds change ( 13 up and 0 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 19 from 42493025 bp to 52498563 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 810124 -- IMAGE clone locate on exon ( blastn )
CH2 (0.67) HK1 (0.89) HK3 (-0.09) HK4 (0.45) HK5 (1.33) HK7 (0.00) HK9 (1.73) HK11 (0.48) HK12 (0.01) HK13 (1.83) HK14 (0.63) HK15 (0.35) HK16 (0.32) HK18 (0.41) HK19 (-0.17) HK20 (0.25) HK21 (0.50) HK22 (-0.25) HK24 (0.99) HK27 (0.21) HK28 (0.20) HK29 (0.42) HK31 (-0.64) HK33 (0.65) HK36 (-0.48) HK37 (0.84) HK38 (-0.03) HK39 (1.10) HK42 (0.78) HK46 (-0.01) HK47 (0.40) HK49 (0.18) HK62 (0.29) HK63 (0.16) HK64 (4.52) HK67 (0.97) HK84 (2.16) HK85 (1.57) SF1 (1.38) SF12 (3.96) SF15 (-0.78) SF17 (0.66) SF18 (2.81) SF21 (0.00) SF22 (3.88) SF23 (-0.00) SF32 (-0.51) SF34 (0.70) SF35 (2.04) SF3 (0.67) SF30 (-0.34) HK2 (-0.81) HK23 (-0.46) HK41 (-0.41) SF4 (0.35) SF8 (-0.59) SF9 (1.64)