OncoDB.HCC Expression View

Gene name : DCT
Ensembl ID ENSG00000080166
Description L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2). [Source:Uniprot/SWISSPROT;Acc:P40126]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
79 percent with 2 folds change ( 1 up and 42 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 13 from 88887559 bp to 98929924 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 753104 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.99) HK1 (-1.32) HK3 (-2.68) HK4 (-3.20) HK5 (-1.67) HK7 (-1.91) HK9 (-1.69) HK11 (-1.39) HK12 (0.12) HK13 (-2.22) HK14 (-0.30) HK15 (-1.11) HK16 (0.46) HK18 (-2.47) HK19 (-1.07) HK20 (-1.41) HK21 (-0.53) HK22 (-2.07) HK24 (-3.29) HK27 (-0.86) HK28 (-1.55) HK29 (0.87) HK31 (-3.33) HK33 (-1.17) HK36 (-2.07) HK37 (-2.48) HK38 (-2.87) HK39 (-1.66) HK42 (-2.14) HK46 (-1.00) HK47 (-4.17) HK49 (0.00) HK62 (0.07) HK63 (-1.54) HK64 (-4.16) HK67 (-2.19) HK84 (-2.46) HK85 (-0.71) SF1 (-3.76) SF12 (-1.33) SF15 (-2.46) SF17 (-1.96) SF18 (1.10) SF21 (0.00) SF22 (-0.04) SF23 (-0.88) SF32 (0.00) SF34 (-0.46) SF35 (-2.56) SF3 (-2.88) SF30 (-2.26) HK2 (-1.69) HK23 (-1.61) HK41 (-1.82) SF4 (-1.41) SF8 (-1.32) SF9 (-1.05)