OncoDB.HCC Expression View

Gene name : XPO1
Ensembl ID ENSG00000082898
Description Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog). [Source:Uniprot/SWISSPROT;Acc:O14980]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
19 percent with 2 folds change ( 9 up and 2 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 2 from 56558573 bp to 66618922 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 74566 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.28) HK1 (0.18) HK3 (0.13) HK4 (1.26) HK5 (0.29) HK7 (0.33) HK9 (0.53) HK11 (0.80) HK12 (0.26) HK13 (1.16) HK14 (0.99) HK15 (1.00) HK16 (0.20) HK18 (1.40) HK19 (0.41) HK20 (0.23) HK21 (0.15) HK22 (1.16) HK24 (0.19) HK27 (-0.18) HK28 (0.38) HK29 (-0.37) HK31 (1.50) HK33 (1.11) HK36 (-1.87) HK37 (0.70) HK38 (0.98) HK39 (0.45) HK42 (0.62) HK46 (0.50) HK47 (0.44) HK49 (0.45) HK62 (0.12) HK63 (0.93) HK64 (0.40) HK67 (0.82) HK84 (0.90) HK85 (0.78) SF1 (0.91) SF12 (1.25) SF15 (0.59) SF17 (-0.72) SF18 (-2.16) SF21 (-0.91) SF22 (0.08) SF23 (-0.05) SF32 (2.37) SF34 (0.25) SF35 (0.77) SF3 (1.14) SF30 (0.85) HK2 (0.54) HK23 (0.49) HK41 (0.48) SF4 (-0.01) SF8 (-0.03) SF9 (0.68)