OncoDB.HCC Expression View

Gene name : FTL
Ensembl ID ENSG00000087086
Description Ferritin light chain (Ferritin L subunit). [Source:Uniprot/SWISSPROT;Acc:P02792]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
49 percent with 2 folds change ( 23 up and 5 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Proteomic Analysis - - Yokoyama et al., Proteomics 4:21111 (2004)
Links Entrez Gene    
Display nearby genome region Chr 19 from 49160378 bp to 59161850 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1575419 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.64) HK1 (0.37) HK3 (0.61) HK4 (2.50) HK5 (-0.07) HK7 (-0.62) HK9 (-1.05) HK11 (1.58) HK12 (0.03) HK13 (2.70) HK14 (1.88) HK15 (2.31) HK16 (0.67) HK18 (1.80) HK19 (0.05) HK20 (-0.10) HK21 (-0.92) HK22 (0.83) HK24 (1.89) HK27 (0.31) HK28 (0.66) HK29 (0.92) HK31 (0.31) HK33 (-0.46) HK36 (1.03) HK37 (2.41) HK38 (-0.20) HK39 (0.45) HK42 (1.94) HK46 (1.84) HK47 (3.44) HK49 (-1.16) HK62 (-1.85) HK63 (-0.48) HK64 (0.54) HK67 (2.68) HK84 (3.12) HK85 (0.74) SF1 (2.09) SF12 (1.87) SF15 (1.27) SF17 (1.31) SF18 (-0.27) SF21 (-1.71) SF22 (0.63) SF23 (-0.02) SF32 (-3.19) SF34 (0.37) SF35 (1.27) SF3 (1.92) SF30 (0.22) HK2 (1.42) HK23 (0.34) HK41 (1.59) SF4 (0.71) SF8 (0.16) SF9 (0.52)