OncoDB.HCC Expression View

Gene name : RPL6
Ensembl ID ENSG00000089009
Description 60S ribosomal protein L6 (TAX-responsive enhancer element-binding protein 107) (TAXREB107) (Neoplasm-related protein C140). [Source:Uniprot/SWISSPROT;Acc:Q02878]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
26 percent with 2 folds change ( 13 up and 2 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA microarray - - Shirota et al., Hepatology 33:832 (2001)
up     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 12 from 106327380 bp to 116331826 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 884546 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.91) HK1 (0.81) HK3 (0.62) HK4 (0.52) HK5 (0.28) HK7 (-0.66) HK9 (0.90) HK11 (1.31) HK12 (0.68) HK13 (1.10) HK14 (1.30) HK15 (0.73) HK16 (-0.48) HK18 (1.03) HK19 (1.06) HK20 (-0.91) HK21 (0.87) HK22 (1.64) HK24 (-0.09) HK27 (0.30) HK28 (0.44) HK29 (-0.79) HK31 (-0.05) HK33 (0.78) HK36 (1.76) HK37 (2.47) HK38 (1.38) HK39 (0.11) HK42 (0.26) HK46 (0.74) HK47 (3.32) HK49 (0.69) HK62 (-1.48) HK63 (-0.30) HK64 (0.38) HK67 (0.58) HK84 (-0.06) HK85 (0.82) SF1 (0.37) SF12 (0.05) SF15 (1.08) SF17 (-1.46) SF18 (-0.67) SF21 (-0.38) SF22 (0.00) SF23 (-0.86) SF32 (-0.93) SF34 (0.36) SF35 (0.65) SF3 (0.71) SF30 (1.09) HK2 (0.25) HK23 (-0.39) HK41 (0.65) SF4 (0.25) SF8 (-0.55) SF9 (1.99)