OncoDB.HCC Expression View

Gene name : PEBP1
Ensembl ID ENSG00000089220
Description Phosphatidylethanolamine-binding protein 1 (PEBP-1) (Prostatic-binding protein) (HCNPpp) (Neuropolypeptide h3) (Raf kinase inhibitor protein) (RKIP) [Contains: Hippocampal cholinergic neurostimulating peptide (HCNP)]. [Source:Uniprot/SWISSPROT;Acc:P30086]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
15 percent with 2 folds change ( 3 up and 6 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
Links Entrez Gene    
Display nearby genome region Chr 12 from 112058253 bp to 122067770 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 843134 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.51) HK1 (0.13) HK3 (-0.63) HK4 (-0.05) HK5 (-0.53) HK7 (0.28) HK9 (-1.30) HK11 (-0.51) HK12 (-0.62) HK13 (-0.16) HK14 (-0.04) HK15 (-0.14) HK16 (-0.25) HK18 (-0.62) HK19 (0.35) HK20 (-0.09) HK21 (-1.47) HK22 (-0.13) HK24 (-0.29) HK27 (-2.29) HK28 (0.70) HK29 (0.57) HK31 (0.18) HK33 (1.32) HK36 (0.41) HK37 (1.15) HK38 (-0.81) HK39 (-1.50) HK42 (-0.06) HK46 (0.27) HK47 (0.28) HK49 (-1.08) HK62 (-0.35) HK63 (0.32) HK64 (0.20) HK67 (0.41) HK84 (-0.45) HK85 (-0.35) SF1 (-0.16) SF12 (0.78) SF15 (-0.58) SF17 (1.43) SF18 (-0.46) SF21 (-0.02) SF22 (0.33) SF23 (0.07) SF32 (0.52) SF34 (0.70) SF35 (-1.76) SF3 (-0.20) SF30 (-0.19) HK2 (0.54) HK23 (-0.97) HK41 (-0.39) SF4 (-0.46) SF8 (-0.43) SF9 (-0.76)