OncoDB.HCC Expression View

Gene name : RGS1
Ensembl ID ENSG00000090104
Description Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34). [Source:Uniprot/SWISSPROT;Acc:Q08116]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
54 percent with 2 folds change ( 9 up and 11 down in 37 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 1 from 185811480 bp to 195815784 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 361323 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.62) HK1 (0.00) HK3 (0.00) HK4 (0.00) HK5 (-1.96) HK7 (-0.92) HK9 (-2.99) HK11 (0.00) HK12 (0.00) HK13 (0.00) HK14 (0.00) HK15 (0.00) HK16 (0.00) HK18 (-0.42) HK19 (-0.77) HK20 (-1.29) HK21 (0.78) HK22 (0.25) HK24 (0.00) HK27 (0.00) HK28 (0.00) HK29 (-0.69) HK31 (0.00) HK33 (0.00) HK36 (0.00) HK37 (2.20) HK38 (-1.33) HK39 (1.57) HK42 (0.00) HK46 (-1.05) HK47 (-1.42) HK49 (0.53) HK62 (1.41) HK63 (-1.56) HK64 (-1.28) HK67 (0.56) HK84 (0.98) HK85 (2.45) SF1 (0.46) SF12 (0.45) SF15 (-0.49) SF17 (-0.51) SF18 (0.29) SF21 (1.58) SF22 (4.42) SF23 (-2.43) SF32 (0.00) SF34 (-0.29) SF35 (0.50) SF3 (0.00) SF30 (2.71) HK2 (0.00) HK23 (0.00) HK41 (-2.68) SF4 (2.21) SF8 (-0.22) SF9 (3.03)