OncoDB.HCC Expression View

Gene name : LYZ
Ensembl ID ENSG00000090382
Description Lysozyme C precursor (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C). [Source:Uniprot/SWISSPROT;Acc:P61626]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
59 percent with 2 folds change ( 29 up and 5 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Mol Cell Proteomics 3:399 (2004)
Links Entrez Gene    
Display nearby genome region Chr 12 from 63028401 bp to 73034280 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 845361 -- IMAGE clone locate on exon ( blastn )
897896 -- IMAGE clone locate on exon ( blastn )
897992 -- IMAGE clone locate on exon ( blastn )
293925 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.37) HK1 (3.77) HK3 (0.38) HK4 (3.57) HK5 (3.30) HK7 (0.71) HK9 (-0.15) HK11 (4.44) HK12 (1.25) HK13 (-0.81) HK14 (5.03) HK15 (0.32) HK16 (4.02) HK18 (0.20) HK19 (2.89) HK20 (-0.57) HK21 (0.31) HK22 (-0.65) HK24 (4.64) HK27 (2.37) HK28 (-0.77) HK29 (-0.32) HK31 (-0.39) HK33 (-0.10) HK36 (3.05) HK37 (4.09) HK38 (0.40) HK39 (1.29) HK42 (4.48) HK46 (1.62) HK47 (4.92) HK49 (2.23) HK62 (1.53) HK63 (-1.01) HK64 (-1.53) HK67 (-0.38) HK84 (1.15) HK85 (0.51) SF1 (4.88) SF12 (0.34) SF15 (-1.24) SF17 (-3.05) SF18 (4.58) SF21 (1.15) SF22 (1.33) SF23 (-0.92) SF32 (-0.29) SF34 (0.33) SF35 (2.33) SF3 (2.54) SF30 (0.06) HK2 (1.77) HK23 (1.08) HK41 (-1.38) SF4 (0.77) SF8 (3.19) SF9 (2.14)