OncoDB.HCC Expression View

Gene name : ITGA6
Ensembl ID ENSG00000091409
Description Integrin alpha-6 precursor (VLA-6) (CD49f antigen) [Contains: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain]. [Source:Uniprot/SWISSPROT;Acc:P23229]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
58 percent with 2 folds change ( 23 up and 0 down in 39 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 2 from 168000616 bp to 178079256 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 44814 -- IMAGE clone locate on exon ( tblastx )
73784 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.70) HK3 (0.23) HK4 (1.54) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (1.27) HK12 (0.09) HK13 (0.99) HK14 (0.12) HK15 (-0.28) HK16 (0.00) HK18 (1.20) HK19 (0.19) HK20 (0.68) HK21 (-0.02) HK22 (-0.26) HK24 (0.91) HK27 (1.11) HK28 (1.32) HK29 (1.49) HK31 (1.32) HK33 (2.21) HK36 (0.93) HK37 (2.13) HK38 (1.22) HK39 (1.09) HK42 (2.44) HK46 (0.00) HK47 (0.00) HK49 (0.00) HK62 (0.86) HK63 (0.20) HK64 (2.89) HK67 (1.14) HK84 (1.92) HK85 (1.06) SF1 (1.07) SF12 (2.40) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (2.42) SF34 (0.85) SF35 (1.44) SF3 (2.53) SF30 (-0.37) HK2 (3.06) HK23 (0.00) HK41 (1.21) SF4 (0.00) SF8 (0.00) SF9 (0.00)