OncoDB.HCC Expression View

Gene name : TF
Ensembl ID ENSG00000091513
Description Serotransferrin precursor (Transferrin) (Siderophilin) (Beta-1-metal- binding globulin). [Source:Uniprot/SWISSPROT;Acc:P02787]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
70 percent with 2 folds change ( 7 up and 31 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
Links Entrez Gene    
Display nearby genome region Chr 3 from 129947925 bp to 139980325 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 292637 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.23) HK1 (-1.51) HK3 (-1.65) HK4 (-4.79) HK5 (-1.55) HK7 (-2.42) HK9 (-1.40) HK11 (-0.05) HK12 (-1.12) HK13 (-1.28) HK14 (-2.36) HK15 (-1.96) HK16 (-0.14) HK18 (-0.35) HK19 (-0.21) HK20 (-2.11) HK21 (-0.73) HK22 (0.53) HK24 (-0.45) HK27 (-1.10) HK28 (-3.53) HK29 (-0.73) HK31 (-2.31) HK33 (-3.09) HK36 (0.00) HK37 (-3.64) HK38 (-1.87) HK39 (0.96) HK42 (0.00) HK46 (-0.77) HK47 (-4.02) HK49 (2.24) HK62 (1.61) HK63 (0.00) HK64 (-2.06) HK67 (-2.50) HK84 (0.35) HK85 (1.14) SF1 (-0.43) SF12 (-4.86) SF15 (-3.12) SF17 (-2.38) SF18 (0.59) SF21 (2.71) SF22 (3.67) SF23 (-1.89) SF32 (-2.21) SF34 (0.45) SF35 (-0.47) SF3 (-4.18) SF30 (2.54) HK2 (-1.08) HK23 (-1.48) HK41 (0.28) SF4 (2.52) SF8 (-1.78) SF9 (-1.46)