OncoDB.HCC Expression View

Gene name : SCD
Ensembl ID ENSG00000099194
Description Acyl-CoA desaturase (EC 1.14.19.1) (Stearoyl-CoA desaturase) (Fatty acid desaturase) (Delta(9)-desaturase). [Source:Uniprot/SWISSPROT;Acc:O00767]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
78 percent with 2 folds change ( 35 up and 10 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 10 from 97096762 bp to 107114577 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 123474 -- IMAGE clone locate on exon ( tblastx )
795242 -- IMAGE clone locate on exon ( tblastx )
810711 -- IMAGE clone locate on exon ( tblastx )
CH2 (2.51) HK1 (3.62) HK3 (-2.70) HK4 (0.98) HK5 (4.42) HK7 (2.29) HK9 (-1.35) HK11 (2.38) HK12 (3.53) HK13 (3.36) HK14 (2.83) HK15 (3.58) HK16 (1.14) HK18 (2.34) HK19 (4.00) HK20 (2.90) HK21 (-1.20) HK22 (-1.14) HK24 (1.78) HK27 (0.29) HK28 (0.27) HK29 (1.75) HK31 (-0.12) HK33 (3.40) HK36 (0.48) HK37 (2.62) HK38 (-1.98) HK39 (3.16) HK42 (1.99) HK46 (2.81) HK47 (2.60) HK49 (2.56) HK62 (-1.06) HK63 (0.26) HK64 (2.71) HK67 (1.21) HK84 (3.44) HK85 (3.21) SF1 (1.09) SF12 (3.04) SF15 (-1.01) SF17 (0.13) SF18 (3.56) SF21 (0.98) SF22 (3.07) SF23 (-1.12) SF32 (1.71) SF34 (-7.86) SF35 (2.86) SF3 (4.90) SF30 (-1.41) HK2 (5.01) HK23 (1.50) HK41 (-0.24) SF4 (0.82) SF8 (0.64) SF9 (0.61)