OncoDB.HCC Expression View

Gene name : IGLV4-3
Ensembl ID ENSG00000100208
Description Ig lambda chain C regions. [Source:Uniprot/SWISSPROT;Acc:P01842]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
78 percent with 2 folds change ( 9 up and 36 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Display nearby genome region Chr 22 from 16294430 bp to 26578968 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 66560 -- IMAGE clone locate on exon ( tblastx )
80796 -- IMAGE clone locate on exon ( tblastx )
154809 -- IMAGE clone locate on exon ( tblastx )
155620 -- IMAGE clone locate on exon ( tblastx )
236124 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.61) HK1 (-4.18) HK3 (-1.29) HK4 (-4.61) HK5 (-4.89) HK7 (-0.23) HK9 (-4.30) HK11 (1.15) HK12 (-2.05) HK13 (-1.86) HK14 (-5.00) HK15 (-0.29) HK16 (1.60) HK18 (-0.12) HK19 (-1.01) HK20 (-3.00) HK21 (0.09) HK22 (-2.61) HK24 (-2.47) HK27 (-0.23) HK28 (-1.45) HK29 (-3.15) HK31 (-3.64) HK33 (-4.14) HK36 (-3.48) HK37 (-5.37) HK38 (-1.59) HK39 (2.54) HK42 (-4.23) HK46 (-0.95) HK47 (-1.83) HK49 (2.61) HK62 (0.59) HK63 (-5.70) HK64 (-3.22) HK67 (-1.67) HK84 (-0.56) HK85 (-1.36) SF1 (-4.26) SF12 (-3.26) SF15 (-3.04) SF17 (-5.53) SF18 (-0.42) SF21 (1.64) SF22 (7.46) SF23 (-1.78) SF32 (-3.78) SF34 (0.22) SF35 (3.04) SF3 (0.68) SF30 (5.12) HK2 (-1.54) HK23 (-2.05) HK41 (-5.95) SF4 (-0.98) SF8 (-3.78) SF9 (1.28)