OncoDB.HCC Expression View

Gene name : CDKN3
Ensembl ID ENSG00000100526
Description Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1). [Source:Uniprot/SWISSPROT;Acc:Q16667]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
76 percent with 2 folds change ( 35 up and 3 down in 50 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 14 from 48933423 bp to 58956682 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 700792 -- IMAGE clone locate on exon ( tblastx )
CH2 (-4.59) HK1 (1.10) HK3 (4.67) HK4 (2.21) HK5 (0.33) HK7 (1.97) HK9 (2.95) HK11 (4.15) HK12 (1.74) HK13 (2.12) HK14 (1.89) HK15 (0.23) HK16 (1.17) HK18 (1.54) HK19 (0.00) HK20 (1.46) HK21 (0.00) HK22 (3.15) HK24 (3.28) HK27 (3.65) HK28 (0.71) HK29 (0.00) HK31 (-2.79) HK33 (1.93) HK36 (2.34) HK37 (0.93) HK38 (1.22) HK39 (4.09) HK42 (3.14) HK46 (2.59) HK47 (2.53) HK49 (1.71) HK62 (1.98) HK63 (3.65) HK64 (3.00) HK67 (1.24) HK84 (0.00) HK85 (3.19) SF1 (-0.50) SF12 (5.25) SF15 (0.00) SF17 (1.52) SF18 (0.00) SF21 (0.00) SF22 (-6.29) SF23 (0.46) SF32 (0.00) SF34 (2.29) SF35 (0.00) SF3 (3.31) SF30 (10.26) HK2 (0.00) HK23 (2.03) HK41 (0.00) SF4 (0.93) SF8 (0.77) SF9 (2.31)