OncoDB.HCC Expression View

Gene name : SLC10A1
Ensembl ID ENSG00000100652
Description Sodium/bile acid cotransporter (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (Solute carrier family 10 member 1). [Source:Uniprot/SWISSPROT;Acc:Q14973]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
58 percent with 2 folds change ( 3 up and 27 down in 51 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- RT-PCR, Western, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 14 from 64312305 bp to 74333707 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 83444 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-1.53) HK3 (-0.91) HK4 (-0.65) HK5 (-3.72) HK7 (-1.11) HK9 (0.26) HK11 (-1.29) HK12 (-1.61) HK13 (-0.73) HK14 (-4.09) HK15 (-2.02) HK16 (-1.04) HK18 (-1.43) HK19 (-2.19) HK20 (-0.10) HK21 (-2.42) HK22 (-0.06) HK24 (0.20) HK27 (-0.44) HK28 (-0.17) HK29 (0.27) HK31 (1.01) HK33 (0.80) HK36 (-1.55) HK37 (-2.55) HK38 (-1.01) HK39 (-2.74) HK42 (-2.17) HK46 (-2.63) HK47 (-5.76) HK49 (-1.39) HK62 (-0.46) HK63 (-0.50) HK64 (0.19) HK67 (0.00) HK84 (0.00) HK85 (-2.90) SF1 (-2.29) SF12 (0.00) SF15 (-3.62) SF17 (2.28) SF18 (0.00) SF21 (-0.58) SF22 (0.29) SF23 (0.35) SF32 (2.08) SF34 (0.49) SF35 (-1.17) SF3 (0.00) SF30 (-4.56) HK2 (-3.42) HK23 (-0.11) HK41 (-1.67) SF4 (-0.35) SF8 (-0.14) SF9 (-2.31)