OncoDB.HCC Expression View

Gene name : MAPRE1
Ensembl ID ENSG00000101367
Description Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1). [Source:Uniprot/SWISSPROT;Acc:Q15691]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
31 percent with 2 folds change ( 5 up and 6 down in 35 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 20 from 25871395 bp to 35901872 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 428223 -- IMAGE clone locate on exon ( tblastx )
1474323 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.26) HK1 (0.00) HK3 (-3.39) HK4 (0.30) HK5 (0.08) HK7 (-0.21) HK9 (0.35) HK11 (0.00) HK12 (-0.07) HK13 (0.52) HK14 (1.11) HK15 (-0.78) HK16 (0.00) HK18 (0.41) HK19 (0.00) HK20 (0.48) HK21 (0.00) HK22 (-0.33) HK24 (0.00) HK27 (0.00) HK28 (-0.43) HK29 (-1.23) HK31 (0.00) HK33 (0.00) HK36 (0.00) HK37 (0.00) HK38 (1.96) HK39 (0.00) HK42 (-0.11) HK46 (-0.54) HK47 (1.67) HK49 (-0.69) HK62 (0.87) HK63 (0.00) HK64 (0.00) HK67 (-0.56) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (-0.40) SF17 (-0.48) SF18 (-1.37) SF21 (0.00) SF22 (-1.73) SF23 (0.26) SF32 (2.31) SF34 (-1.50) SF35 (0.00) SF3 (-6.08) SF30 (0.00) HK2 (-0.35) HK23 (-0.24) HK41 (0.00) SF4 (-0.28) SF8 (0.16) SF9 (1.13)