OncoDB.HCC Expression View

Gene name : RBM3
Ensembl ID ENSG00000102317
Description Putative RNA-binding protein 3 (RNA-binding motif protein 3) (RNPL). [Source:Uniprot/SWISSPROT;Acc:P98179]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
38 percent with 2 folds change ( 21 up and 0 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr X from 43317780 bp to 53322398 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 380797 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (1.12) HK3 (0.55) HK4 (1.35) HK5 (0.15) HK7 (0.28) HK9 (0.52) HK11 (1.83) HK12 (0.84) HK13 (0.24) HK14 (0.96) HK15 (1.45) HK16 (0.89) HK18 (0.49) HK19 (1.45) HK20 (-0.32) HK21 (1.73) HK22 (1.33) HK24 (0.48) HK27 (0.35) HK28 (-0.13) HK29 (-0.20) HK31 (-0.54) HK33 (-0.62) HK36 (1.04) HK37 (1.02) HK38 (1.36) HK39 (0.97) HK42 (-0.17) HK46 (-0.20) HK47 (2.32) HK49 (1.73) HK62 (-0.08) HK63 (-0.62) HK64 (0.25) HK67 (-0.01) HK84 (1.60) HK85 (0.62) SF1 (0.00) SF12 (2.76) SF15 (3.35) SF17 (0.37) SF18 (0.33) SF21 (1.02) SF22 (1.11) SF23 (-0.28) SF32 (0.07) SF34 (-0.17) SF35 (0.77) SF3 (0.78) SF30 (1.63) HK2 (1.91) HK23 (-0.18) HK41 (0.99) SF4 (0.45) SF8 (1.80) SF9 (2.15)