OncoDB.HCC Expression View

Gene name : NME3
Ensembl ID ENSG00000103024
Description Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) (DR-nm23). [Source:Uniprot/SWISSPROT;Acc:Q13232]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
75 percent with 2 folds change ( 0 up and 42 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Honda et al., Gastroenterology 120:955(2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 16 from 0 bp to 6761711 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 726658 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-1.28) HK3 (-1.71) HK4 (-3.57) HK5 (-0.54) HK7 (-1.14) HK9 (-1.77) HK11 (-2.05) HK12 (-2.68) HK13 (-2.08) HK14 (-2.65) HK15 (-2.20) HK16 (-1.09) HK18 (-1.78) HK19 (-3.12) HK20 (-1.05) HK21 (-1.54) HK22 (-0.33) HK24 (-1.67) HK27 (-2.50) HK28 (-0.93) HK29 (-0.33) HK31 (-0.42) HK33 (-0.91) HK36 (-1.17) HK37 (-2.69) HK38 (-1.76) HK39 (-2.42) HK42 (-2.80) HK46 (-2.02) HK47 (-2.05) HK49 (-1.75) HK62 (-0.60) HK63 (-2.80) HK64 (-2.50) HK67 (-0.78) HK84 (-1.68) HK85 (-1.16) SF1 (-2.47) SF12 (-2.60) SF15 (-0.91) SF17 (-0.76) SF18 (-2.73) SF21 (0.27) SF22 (-0.97) SF23 (-0.62) SF32 (-3.03) SF34 (-0.26) SF35 (-1.90) SF3 (-3.14) SF30 (-1.42) HK2 (-1.92) HK23 (-1.71) HK41 (-1.53) SF4 (-1.27) SF8 (-1.48) SF9 (-2.03)