OncoDB.HCC Expression View

Gene name : RBL2
Ensembl ID ENSG00000103479
Description Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2). [Source:Uniprot/SWISSPROT;Acc:Q08999]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
10 percent with 2 folds change ( 0 up and 5 down in 46 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 16 from 47025862 bp to 57083060 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 280752 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.77) HK1 (-0.85) HK3 (-0.90) HK4 (-0.88) HK5 (-0.76) HK7 (-0.45) HK9 (-0.94) HK11 (-0.12) HK12 (-0.27) HK13 (-1.03) HK14 (-1.28) HK15 (-0.93) HK16 (0.50) HK18 (0.00) HK19 (-0.53) HK20 (-0.04) HK21 (0.23) HK22 (0.21) HK24 (-0.60) HK27 (-0.43) HK28 (0.49) HK29 (0.00) HK31 (0.00) HK33 (0.00) HK36 (0.00) HK37 (-0.90) HK38 (0.00) HK39 (-0.52) HK42 (0.00) HK46 (-0.45) HK47 (-1.07) HK49 (-0.37) HK62 (0.32) HK63 (0.00) HK64 (0.17) HK67 (-0.79) HK84 (-0.73) HK85 (-0.39) SF1 (0.00) SF12 (-1.49) SF15 (0.12) SF17 (-0.58) SF18 (-0.80) SF21 (0.00) SF22 (-0.96) SF23 (-0.02) SF32 (0.25) SF34 (-0.13) SF35 (0.29) SF3 (0.00) SF30 (-0.16) HK2 (0.53) HK23 (0.09) HK41 (-0.05) SF4 (0.61) SF8 (-0.32) SF9 (-1.27)