OncoDB.HCC Expression View

Gene name : LAPTM4B
Ensembl ID ENSG00000104341
Description Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta). [Source:Uniprot/SWISSPROT;Acc:Q86VI4]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
63 percent with 2 folds change ( 33 up and 3 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 8 from 93856461 bp to 103934002 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 429959 -- IMAGE clone locate on exon ( tblastx )
949988 -- IMAGE clone locate on exon ( tblastx )
CH2 (2.98) HK1 (0.29) HK3 (2.22) HK4 (1.48) HK5 (0.43) HK7 (0.78) HK9 (0.33) HK11 (1.77) HK12 (1.47) HK13 (1.70) HK14 (1.69) HK15 (3.09) HK16 (0.11) HK18 (2.10) HK19 (1.38) HK20 (-2.86) HK21 (1.17) HK22 (-0.01) HK24 (2.53) HK27 (4.00) HK28 (-0.93) HK29 (-1.99) HK31 (0.08) HK33 (1.53) HK36 (0.05) HK37 (4.23) HK38 (1.02) HK39 (1.71) HK42 (2.62) HK46 (0.77) HK47 (2.69) HK49 (0.48) HK62 (-0.39) HK63 (0.49) HK64 (0.94) HK67 (1.62) HK84 (4.44) HK85 (1.36) SF1 (3.36) SF12 (4.58) SF15 (1.69) SF17 (1.10) SF18 (4.66) SF21 (0.03) SF22 (2.99) SF23 (-1.19) SF32 (0.70) SF34 (-0.30) SF35 (2.80) SF3 (1.38) SF30 (2.04) HK2 (-0.07) HK23 (1.45) HK41 (-0.76) SF4 (0.30) SF8 (0.75) SF9 (3.51)