OncoDB.HCC Expression View

Gene name : ECH1
Ensembl ID ENSG00000104823
Description Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-). [Source:Uniprot/SWISSPROT;Acc:Q13011]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
30 percent with 2 folds change ( 2 up and 15 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Mol Cell Proteomics 3:399 (2004)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
Links Entrez Gene    
Display nearby genome region Chr 19 from 38997908 bp to 49014337 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 769537 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.29) HK1 (-0.72) HK3 (-0.84) HK4 (-0.67) HK5 (-0.50) HK7 (-0.82) HK9 (-0.05) HK11 (-1.30) HK12 (-0.42) HK13 (-0.34) HK14 (-1.36) HK15 (0.16) HK16 (0.32) HK18 (-2.30) HK19 (0.23) HK20 (0.36) HK21 (-1.19) HK22 (0.38) HK24 (0.23) HK27 (-1.56) HK28 (0.23) HK29 (0.00) HK31 (0.02) HK33 (0.78) HK36 (-0.85) HK37 (-0.97) HK38 (-0.23) HK39 (-0.12) HK42 (-1.19) HK46 (-2.36) HK47 (-1.81) HK49 (-0.37) HK62 (0.06) HK63 (-0.11) HK64 (-1.38) HK67 (1.31) HK84 (-2.20) HK85 (-0.35) SF1 (-1.19) SF12 (-1.76) SF15 (-0.99) SF17 (0.27) SF18 (-0.73) SF21 (-0.51) SF22 (-0.70) SF23 (0.28) SF32 (0.90) SF34 (1.06) SF35 (-0.42) SF3 (0.01) SF30 (-1.10) HK2 (0.38) HK23 (-0.85) HK41 (-1.33) SF4 (0.37) SF8 (-0.10) SF9 (-1.73)