OncoDB.HCC Expression View

Gene name : CCNE1
Ensembl ID ENSG00000105173
Description G1/S-specific cyclin-E1. [Source:Uniprot/SWISSPROT;Acc:P24864]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
31 percent with 2 folds change ( 12 up and 2 down in 44 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western, QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 19 from 29994741 bp to 40007056 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 68950 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.32) HK3 (0.85) HK4 (-0.01) HK5 (0.00) HK7 (0.00) HK9 (1.55) HK11 (-0.99) HK12 (-0.25) HK13 (1.23) HK14 (2.75) HK15 (1.84) HK16 (0.05) HK18 (0.31) HK19 (-0.89) HK20 (0.46) HK21 (0.77) HK22 (0.38) HK24 (0.53) HK27 (0.40) HK28 (-0.16) HK29 (0.00) HK31 (3.71) HK33 (0.51) HK36 (-0.52) HK37 (0.01) HK38 (1.60) HK39 (0.69) HK42 (0.00) HK46 (-0.02) HK47 (-1.33) HK49 (0.00) HK62 (1.03) HK63 (2.31) HK64 (-0.86) HK67 (0.00) HK84 (-0.38) HK85 (0.00) SF1 (2.87) SF12 (0.00) SF15 (0.33) SF17 (0.00) SF18 (0.00) SF21 (1.23) SF22 (0.00) SF23 (0.00) SF32 (0.77) SF34 (0.00) SF35 (0.58) SF3 (0.00) SF30 (3.27) HK2 (-1.30) HK23 (3.13) HK41 (0.30) SF4 (0.00) SF8 (-0.06) SF9 (-0.01)