OncoDB.HCC Expression View

Gene name : PDCD5
Ensembl ID ENSG00000105185
Description Programmed cell death protein 5 (Protein TFAR19) (TF-1 cell apoptosis- related gene 19 protein). [Source:Uniprot/SWISSPROT;Acc:O14737]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
8 percent with 2 folds change ( 4 up and 1 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     Oligo Microarray - - Tackels-Horne et al., Cancer 92:395 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 19 from 32763945 bp to 42770046 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 502369 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.60) HK1 (0.42) HK3 (-0.12) HK4 (0.43) HK5 (0.59) HK7 (0.61) HK9 (-0.15) HK11 (0.80) HK12 (0.26) HK13 (-0.01) HK14 (1.17) HK15 (1.79) HK16 (0.76) HK18 (0.75) HK19 (0.22) HK20 (0.10) HK21 (0.81) HK22 (-0.38) HK24 (0.67) HK27 (0.19) HK28 (-0.07) HK29 (-0.17) HK31 (-0.18) HK33 (0.35) HK36 (-0.41) HK37 (1.40) HK38 (0.55) HK39 (0.91) HK42 (0.90) HK46 (0.96) HK47 (-0.50) HK49 (0.39) HK62 (0.22) HK63 (-1.29) HK64 (0.22) HK67 (0.27) HK84 (0.92) HK85 (1.40) SF1 (0.99) SF12 (0.41) SF15 (-0.50) SF17 (-0.15) SF18 (-0.45) SF21 (-0.72) SF22 (0.60) SF23 (-0.41) SF32 (0.75) SF34 (0.70) SF35 (0.78) SF3 (0.77) SF30 (0.60) HK2 (0.41) HK23 (0.80) HK41 (0.04) SF4 (-0.20) SF8 (-0.02) SF9 (0.49)