OncoDB.HCC Expression View

Gene name : EZH2
Ensembl ID ENSG00000106462
Description Enhancer of zeste homolog 2 (ENX-1). [Source:Uniprot/SWISSPROT;Acc:Q15910]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
53 percent with 2 folds change ( 29 up and 1 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 7 from 143135408 bp to 153212347 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 770992 -- IMAGE clone locate on exon ( tblastx )
CH2 (4.46) HK1 (-0.52) HK3 (0.93) HK4 (0.57) HK5 (0.61) HK7 (0.31) HK9 (1.37) HK11 (0.76) HK12 (1.16) HK13 (1.22) HK14 (2.27) HK15 (1.00) HK16 (0.05) HK18 (0.40) HK19 (1.44) HK20 (1.13) HK21 (0.16) HK22 (0.05) HK24 (0.94) HK27 (0.76) HK28 (0.08) HK29 (1.47) HK31 (1.06) HK33 (0.91) HK36 (0.83) HK37 (0.50) HK38 (0.65) HK39 (1.23) HK42 (2.27) HK46 (0.00) HK47 (0.99) HK49 (1.04) HK62 (1.17) HK63 (1.77) HK64 (0.92) HK67 (-0.25) HK84 (1.18) HK85 (2.28) SF1 (-1.88) SF12 (2.63) SF15 (1.19) SF17 (1.82) SF18 (2.15) SF21 (2.41) SF22 (3.63) SF23 (0.26) SF32 (-0.04) SF34 (1.27) SF35 (1.37) SF3 (1.60) SF30 (1.37) HK2 (0.56) HK23 (-0.06) HK41 (1.60) SF4 (0.60) SF8 (-0.03) SF9 (1.65)