OncoDB.HCC Expression View

Gene name : CXCL12
Ensembl ID ENSG00000107562
Description Stromal cell-derived factor 1 precursor (SDF-1) (CXCL12) (Pre-B cell growth-stimulating factor) (PBSF) (hIRH) [Contains: SDF-1-beta(3-72); SDF-1-alpha(3-67)]. [Source:Uniprot/SWISSPROT;Acc:P48061]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
down     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 10 from 39185619 bp to 49200548 bp