OncoDB.HCC Expression View

Gene name : MAWBP_HUMAN
Ensembl ID ENSG00000108187
Description Probable isomerase MAWBP (EC 5.1.-.-) (MAWD-binding protein) (Unknown protein 32 from 2D-page of liver tissue). [Source:Uniprot/SWISSPROT;Acc:P30039]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
66 percent with 2 folds change ( 5 up and 32 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     PCR Array - - Kurokawa et al., J Hepatol. 39:1004 (2003)
down     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
down     Proteomic Analysis - - Blanc et al., Proteomics 5:37788 (2005)
Links Entrez Gene    
Display nearby genome region Chr 10 from 64712423 bp to 74762690 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 39178 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.59) HK1 (-1.21) HK3 (-1.26) HK4 (-3.34) HK5 (0.74) HK7 (1.76) HK9 (0.22) HK11 (-1.58) HK12 (-1.27) HK13 (-0.23) HK14 (-1.43) HK15 (-2.03) HK16 (-1.80) HK18 (-1.70) HK19 (-1.27) HK20 (-1.14) HK21 (0.00) HK22 (0.35) HK24 (-0.71) HK27 (-2.65) HK28 (-4.10) HK29 (-1.22) HK31 (0.77) HK33 (0.99) HK36 (-1.31) HK37 (-2.91) HK38 (-2.55) HK39 (-4.33) HK42 (0.73) HK46 (-2.04) HK47 (-1.70) HK49 (-3.48) HK62 (-1.29) HK63 (0.17) HK64 (-0.79) HK67 (0.98) HK84 (-3.22) HK85 (0.47) SF1 (0.72) SF12 (-3.41) SF15 (-0.64) SF17 (1.72) SF18 (-5.68) SF21 (1.60) SF22 (2.37) SF23 (-1.09) SF32 (-4.22) SF34 (1.15) SF35 (-0.90) SF3 (-3.60) SF30 (-1.43) HK2 (-0.45) HK23 (-1.70) HK41 (-2.70) SF4 (-0.16) SF8 (-0.51) SF9 (-4.64)