OncoDB.HCC Expression View

Gene name : GALK1
Ensembl ID ENSG00000108479
Description Galactokinase (EC 2.7.1.6) (Galactose kinase). [Source:Uniprot/SWISSPROT;Acc:P51570]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 15 up and 0 down in 53 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
up     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene    
Display nearby genome region Chr 17 from 66265613 bp to 76272875 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1608772 -- IMAGE clone locate on exon ( blastn )
CH2 (1.00) HK1 (-0.15) HK3 (1.00) HK4 (0.25) HK5 (-0.29) HK7 (-0.01) HK9 (0.27) HK11 (0.36) HK12 (0.64) HK13 (0.07) HK14 (1.04) HK15 (-0.17) HK16 (0.10) HK18 (0.82) HK19 (0.46) HK20 (0.12) HK21 (0.91) HK22 (0.53) HK24 (0.36) HK27 (0.67) HK28 (0.82) HK29 (0.54) HK31 (0.58) HK33 (1.11) HK36 (-0.65) HK37 (1.41) HK38 (-0.21) HK39 (1.25) HK42 (1.48) HK46 (0.00) HK47 (0.00) HK49 (0.00) HK62 (0.57) HK63 (-0.01) HK64 (-0.29) HK67 (1.05) HK84 (1.33) HK85 (0.97) SF1 (1.16) SF12 (1.07) SF15 (-0.04) SF17 (-0.93) SF18 (0.26) SF21 (-0.26) SF22 (1.34) SF23 (0.08) SF32 (0.48) SF34 (1.08) SF35 (0.70) SF3 (1.11) SF30 (1.02) HK2 (0.23) HK23 (-0.20) HK41 (0.24) SF4 (0.00) SF8 (-0.64) SF9 (1.75)