OncoDB.HCC Expression View

Gene name : CCL2
Ensembl ID ENSG00000108691
Description Small inducible cytokine A2 precursor (CCL2) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte secretory protein JE) (HC11). [Source:Uniprot/SWISSPROT;Acc:P13500]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
75 percent with 2 folds change ( 1 up and 42 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 17 from 24606409 bp to 34608329 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 108837 -- IMAGE clone locate on exon ( tblastx )
768561 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.32) HK1 (-1.17) HK3 (-0.64) HK4 (-0.82) HK5 (-2.15) HK7 (-2.43) HK9 (-2.84) HK11 (-0.28) HK12 (-2.18) HK13 (-3.81) HK14 (-1.20) HK15 (-1.05) HK16 (-1.23) HK18 (-2.01) HK19 (-2.16) HK20 (-2.93) HK21 (0.76) HK22 (-1.04) HK24 (-2.59) HK27 (0.79) HK28 (-2.00) HK29 (-2.54) HK31 (-1.06) HK33 (-1.39) HK36 (-0.64) HK37 (-1.83) HK38 (-2.54) HK39 (0.12) HK42 (-3.44) HK46 (-2.70) HK47 (-1.75) HK49 (0.69) HK62 (-1.48) HK63 (-3.15) HK64 (-1.75) HK67 (-1.80) HK84 (-2.00) HK85 (-2.92) SF1 (-3.73) SF12 (-2.02) SF15 (-2.82) SF17 (-3.55) SF18 (-2.06) SF21 (1.12) SF22 (-0.59) SF23 (-5.90) SF32 (-2.72) SF34 (-1.23) SF35 (-0.40) SF3 (-2.03) SF30 (-0.97) HK2 (-1.96) HK23 (0.02) HK41 (-1.32) SF4 (-0.89) SF8 (-0.38) SF9 (-1.13)