OncoDB.HCC Expression View

Gene name : SLC9A3R1
Ensembl ID ENSG00000109062
Description Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory f [Source:Uniprot/SWISSPROT;Acc:O14745]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
27 percent with 2 folds change ( 14 up and 1 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 17 from 65256581 bp to 75277084 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 773286 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.30) HK1 (0.57) HK3 (0.65) HK4 (0.00) HK5 (1.04) HK7 (0.84) HK9 (0.74) HK11 (0.33) HK12 (0.25) HK13 (0.59) HK14 (1.55) HK15 (1.75) HK16 (0.73) HK18 (0.23) HK19 (0.14) HK20 (0.19) HK21 (0.33) HK22 (0.51) HK24 (-0.51) HK27 (0.06) HK28 (1.73) HK29 (0.33) HK31 (1.51) HK33 (0.23) HK36 (-0.65) HK37 (2.03) HK38 (-0.10) HK39 (1.03) HK42 (1.46) HK46 (0.08) HK47 (0.24) HK49 (-0.90) HK62 (-1.31) HK63 (0.95) HK64 (2.54) HK67 (0.85) HK84 (0.64) HK85 (-0.02) SF1 (0.69) SF12 (1.74) SF15 (0.44) SF17 (0.34) SF18 (0.34) SF21 (0.18) SF22 (0.51) SF23 (0.05) SF32 (0.13) SF34 (-0.10) SF35 (1.34) SF3 (0.87) SF30 (1.62) HK2 (1.63) HK23 (0.23) HK41 (0.40) SF4 (0.27) SF8 (0.00) SF9 (1.56)