OncoDB.HCC Expression View

Gene name : HSPA8
Ensembl ID ENSG00000109971
Description Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8). [Source:Uniprot/SWISSPROT;Acc:P11142]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
22 percent with 2 folds change ( 8 up and 4 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
Links Entrez Gene    
Display nearby genome region Chr 11 from 117433411 bp to 127438054 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 884719 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.57) HK1 (0.47) HK3 (0.39) HK4 (0.98) HK5 (0.30) HK7 (-1.34) HK9 (0.11) HK11 (1.28) HK12 (-0.17) HK13 (0.73) HK14 (0.83) HK15 (1.50) HK16 (0.00) HK18 (0.53) HK19 (0.95) HK20 (-0.47) HK21 (0.96) HK22 (1.81) HK24 (0.50) HK27 (0.50) HK28 (0.32) HK29 (0.70) HK31 (-0.33) HK33 (0.58) HK36 (0.79) HK37 (0.00) HK38 (1.54) HK39 (-0.25) HK42 (0.05) HK46 (-0.15) HK47 (3.18) HK49 (0.31) HK62 (-1.42) HK63 (-0.32) HK64 (0.09) HK67 (0.57) HK84 (0.00) HK85 (-0.68) SF1 (-1.21) SF12 (-0.07) SF15 (0.59) SF17 (-1.80) SF18 (1.02) SF21 (-0.37) SF22 (-0.58) SF23 (-0.59) SF32 (-0.05) SF34 (-0.98) SF35 (0.46) SF3 (-0.23) SF30 (1.06) HK2 (0.11) HK23 (-0.13) HK41 (0.75) SF4 (0.09) SF8 (-0.17) SF9 (1.27)