OncoDB.HCC Expression View

Gene name : SLC22A18
Ensembl ID ENSG00000110628
Description Organic cation transporter-like protein 2 (Imprinted multi-membrane spanning polyspecific transporter-related protein 1) (Efflux transporter-like protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein) (Tumor-suppressing [Source:Uniprot/SWISSPROT;Acc:Q96BI1]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
43 percent with 2 folds change ( 9 up and 14 down in 53 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- SSCP    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 11 from 0 bp to 7903052 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 742862 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.83) HK3 (-0.83) HK4 (-2.21) HK5 (1.90) HK7 (0.13) HK9 (0.00) HK11 (-0.07) HK12 (-0.20) HK13 (-0.43) HK14 (-0.97) HK15 (0.80) HK16 (0.39) HK18 (1.11) HK19 (0.04) HK20 (0.49) HK21 (-0.93) HK22 (-0.05) HK24 (0.20) HK27 (-1.08) HK28 (-0.79) HK29 (-0.08) HK31 (0.91) HK33 (0.00) HK36 (0.08) HK37 (1.03) HK38 (-1.82) HK39 (-1.27) HK42 (-0.87) HK46 (0.88) HK47 (-1.65) HK49 (1.52) HK62 (0.19) HK63 (-1.14) HK64 (-0.27) HK67 (-2.31) HK84 (0.06) HK85 (-2.98) SF1 (0.71) SF12 (0.00) SF15 (-2.37) SF17 (-1.25) SF18 (1.53) SF21 (0.87) SF22 (3.35) SF23 (0.98) SF32 (4.85) SF34 (1.07) SF35 (-1.08) SF3 (-2.24) SF30 (-1.75) HK2 (-0.50) HK23 (0.39) HK41 (1.60) SF4 (0.81) SF8 (0.39) SF9 (-2.67)