OncoDB.HCC Expression View

Gene name : CDKN1B
Ensembl ID ENSG00000111276
Description Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1). [Source:Uniprot/SWISSPROT;Acc:P46527]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
7 percent with 2 folds change ( 3 up and 1 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up/down     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 12 from 7761576 bp to 17766569 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 854668 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.07) HK1 (0.35) HK3 (0.52) HK4 (-0.46) HK5 (0.39) HK7 (0.02) HK9 (0.56) HK11 (-0.30) HK12 (0.06) HK13 (-0.50) HK14 (0.35) HK15 (-0.28) HK16 (0.70) HK18 (-0.21) HK19 (0.34) HK20 (0.00) HK21 (0.35) HK22 (-0.20) HK24 (-0.66) HK27 (0.42) HK28 (0.00) HK29 (0.82) HK31 (0.33) HK33 (0.28) HK36 (0.30) HK37 (-0.01) HK38 (0.22) HK39 (0.46) HK42 (0.52) HK46 (-0.76) HK47 (0.15) HK49 (0.12) HK62 (0.92) HK63 (0.74) HK64 (-0.54) HK67 (0.31) HK84 (-0.75) HK85 (0.99) SF1 (-0.64) SF12 (1.03) SF15 (0.78) SF17 (0.43) SF18 (-0.42) SF21 (1.54) SF22 (0.22) SF23 (0.33) SF32 (-0.09) SF34 (0.44) SF35 (-1.23) SF3 (0.49) SF30 (1.41) HK2 (-0.49) HK23 (-0.47) HK41 (0.63) SF4 (0.53) SF8 (0.04) SF9 (0.19)