OncoDB.HCC Expression View

Gene name : GYS2
Ensembl ID ENSG00000111713
Description Glycogen [starch] synthase, liver (EC 2.4.1.11). [Source:Uniprot/SWISSPROT;Acc:P54840]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
78 percent with 2 folds change ( 5 up and 32 down in 47 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 12 from 16580392 bp to 26648821 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 245920 -- IMAGE clone locate on exon ( tblastx )
CH2 (-4.74) HK1 (-2.35) HK3 (-2.12) HK4 (-4.92) HK5 (0.00) HK7 (-0.84) HK9 (-0.65) HK11 (-2.35) HK12 (-1.11) HK13 (0.07) HK14 (-3.62) HK15 (-3.35) HK16 (-0.86) HK18 (-1.62) HK19 (-2.79) HK20 (0.00) HK21 (-2.58) HK22 (0.65) HK24 (0.16) HK27 (-5.50) HK28 (-2.34) HK29 (-1.09) HK31 (2.47) HK33 (1.10) HK36 (-1.74) HK37 (-3.66) HK38 (-4.45) HK39 (-2.76) HK42 (-1.73) HK46 (-5.26) HK47 (0.00) HK49 (-5.16) HK62 (0.00) HK63 (-1.01) HK64 (-1.73) HK67 (0.00) HK84 (-4.24) HK85 (-0.91) SF1 (1.00) SF12 (0.00) SF15 (-3.34) SF17 (1.21) SF18 (0.00) SF21 (0.74) SF22 (0.00) SF23 (0.93) SF32 (3.87) SF34 (-1.38) SF35 (0.00) SF3 (-4.46) SF30 (-4.99) HK2 (-4.41) HK23 (0.16) HK41 (-1.27) SF4 (0.00) SF8 (-2.27) SF9 (-5.95)