OncoDB.HCC Expression View

Gene name : VEGFA
Ensembl ID ENSG00000112715
Description Vascular endothelial growth factor A precursor (VEGF-A) (Vascular permeability factor) (VPF). [Source:Uniprot/SWISSPROT;Acc:P15692]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
21 percent with 2 folds change ( 9 up and 3 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 6 from 38845924 bp to 48862202 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 34778 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.26) HK1 (0.41) HK3 (-0.16) HK4 (0.00) HK5 (0.00) HK7 (0.34) HK9 (0.75) HK11 (0.04) HK12 (0.40) HK13 (0.09) HK14 (2.06) HK15 (0.79) HK16 (-0.42) HK18 (-0.59) HK19 (0.27) HK20 (-0.25) HK21 (1.02) HK22 (0.15) HK24 (-0.06) HK27 (0.60) HK28 (-0.69) HK29 (-0.13) HK31 (0.32) HK33 (-0.55) HK36 (1.98) HK37 (0.72) HK38 (0.81) HK39 (1.33) HK42 (1.56) HK46 (-1.12) HK47 (-0.35) HK49 (-0.45) HK62 (0.60) HK63 (0.02) HK64 (0.29) HK67 (0.14) HK84 (-0.51) HK85 (-0.17) SF1 (1.21) SF12 (0.75) SF15 (1.62) SF17 (-0.52) SF18 (-1.54) SF21 (0.20) SF22 (0.06) SF23 (-0.69) SF32 (-0.61) SF34 (0.51) SF35 (-0.61) SF3 (1.38) SF30 (1.55) HK2 (-0.33) HK23 (0.30) HK41 (-0.25) SF4 (-1.08) SF8 (-0.07) SF9 (-0.42)