OncoDB.HCC Expression View

Gene name : HBEGF
Ensembl ID ENSG00000113070
Description Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R). [Source:Uniprot/SWISSPROT;Acc:Q99075]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
37 percent with 2 folds change ( 4 up and 15 down in 51 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern, IHC    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 5 from 134692615 bp to 144706359 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 35828 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.21) HK1 (0.91) HK3 (-0.28) HK4 (-1.24) HK5 (0.69) HK7 (0.00) HK9 (-0.81) HK11 (-0.71) HK12 (-0.66) HK13 (-1.04) HK14 (-0.64) HK15 (-0.21) HK16 (-0.73) HK18 (-0.95) HK19 (-1.53) HK20 (-0.28) HK21 (0.75) HK22 (-0.63) HK24 (-1.55) HK27 (1.13) HK28 (-1.13) HK29 (-0.42) HK31 (0.86) HK33 (1.27) HK36 (0.15) HK37 (-0.62) HK38 (-0.45) HK39 (-1.02) HK42 (-0.95) HK46 (-1.58) HK47 (-0.01) HK49 (0.41) HK62 (0.38) HK63 (0.01) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (-0.99) SF1 (-0.37) SF12 (0.49) SF15 (-1.02) SF17 (-1.11) SF18 (0.00) SF21 (1.25) SF22 (1.09) SF23 (0.00) SF32 (-1.12) SF34 (-1.62) SF35 (-1.20) SF3 (-0.16) SF30 (-1.39) HK2 (-0.81) HK23 (-0.11) HK41 (-0.89) SF4 (-1.03) SF8 (0.31) SF9 (0.27)