OncoDB.HCC Expression View

Gene name : COL7A1
Ensembl ID ENSG00000114270
Description Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen). [Source:Uniprot/SWISSPROT;Acc:Q02388]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
44 percent with 2 folds change ( 17 up and 4 down in 47 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 3 from 43576510 bp to 53607704 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 897768 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (3.30) HK3 (-0.45) HK4 (4.48) HK5 (3.92) HK7 (-2.09) HK9 (1.79) HK11 (-0.88) HK12 (-0.70) HK13 (0.00) HK14 (2.18) HK15 (0.00) HK16 (0.00) HK18 (1.26) HK19 (-0.27) HK20 (-0.90) HK21 (3.12) HK22 (-0.08) HK24 (-0.20) HK27 (0.30) HK28 (0.39) HK29 (0.92) HK31 (-0.61) HK33 (0.43) HK36 (0.00) HK37 (-1.02) HK38 (0.22) HK39 (-0.33) HK42 (0.00) HK46 (1.63) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (0.00) HK64 (1.86) HK67 (0.40) HK84 (1.95) HK85 (0.74) SF1 (1.89) SF12 (0.70) SF15 (-0.68) SF17 (3.42) SF18 (-0.54) SF21 (-1.55) SF22 (3.71) SF23 (1.08) SF32 (0.91) SF34 (-0.39) SF35 (1.29) SF3 (0.00) SF30 (-1.62) HK2 (0.04) HK23 (0.78) HK41 (0.00) SF4 (1.35) SF8 (2.16) SF9 (0.94)