OncoDB.HCC Expression View

Gene name : ACY1
Ensembl ID ENSG00000114786
Description Aminoacylase-1 (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (ACY-1). [Source:Uniprot/SWISSPROT;Acc:Q03154]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
38 percent with 2 folds change ( 2 up and 19 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
down     Proteomic Analysis - - Blanc et al., Proteomics 5:37788 (2005)
Links Entrez Gene    
Display nearby genome region Chr 3 from 46992535 bp to 56998223 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 741988 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.07) HK3 (-0.75) HK4 (-1.30) HK5 (0.81) HK7 (-0.49) HK9 (-1.90) HK11 (-1.14) HK12 (-0.09) HK13 (-0.54) HK14 (-2.43) HK15 (-0.70) HK16 (0.74) HK18 (-0.62) HK19 (0.00) HK20 (-0.08) HK21 (-1.74) HK22 (-0.28) HK24 (-0.30) HK27 (-2.07) HK28 (0.11) HK29 (-0.05) HK31 (-0.32) HK33 (1.12) HK36 (-0.25) HK37 (-1.55) HK38 (-1.79) HK39 (-1.58) HK42 (-1.44) HK46 (-0.82) HK47 (-2.65) HK49 (-1.95) HK62 (0.12) HK63 (-0.65) HK64 (-0.48) HK67 (-0.03) HK84 (-1.27) HK85 (-0.31) SF1 (-0.68) SF12 (-1.51) SF15 (-1.57) SF17 (0.85) SF18 (-0.34) SF21 (0.00) SF22 (-0.37) SF23 (0.82) SF32 (1.50) SF34 (-0.05) SF35 (-1.84) SF3 (-0.80) SF30 (-3.85) HK2 (0.09) HK23 (0.08) HK41 (-1.27) SF4 (-0.39) SF8 (-0.23) SF9 (-1.21)